{"metadata":{"accession":"PF20214","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR046481","hierarchy":null,"name":{"name":"Domain of unknown function (DUF6574)","short":"DUF6574"},"description":[{"text":"<p>This entry represents a domain of unknown function in bacterial proteins, mainly from Firmicutes. Proteins in this family are typically between 116 and 320 amino acids in length. Many members are thought to contain a zinc ribbon domain at the N-terminal. This entry includes Uncharacterized protein YebC from Bacillus subtilis which contains transmembrane helices. This entry shows structural similarity to the Yip1 domain [pfam:PF04893].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0112","name":"Yip1"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":3,"interactions":0,"matches":356,"pathways":0,"proteins":356,"proteomes":337,"sets":1,"structural_models":{"alphafold":223},"structures":0,"taxa":557},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":3,"alignment:full":136},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}