This domain is functionally uncharacterised and is found in proteins from bacteria and archaea. This domain is found in Protein LicC (swiss:P14183), a CTP:phosphocholine cytidylyltransferase involved in LPS biosynthesis. Members containing this domain are annotated as nucleotidyltransferases. It is probable that this domain has a Rossmann like fold.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0110","name":"GT-A"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":3,"interactions":0,"matches":20,"pathways":0,"proteins":20,"proteomes":19,"sets":1,"structural_models":{"alphafold":17},"structures":0,"taxa":89},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":7,"alignment:full":19},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}