{"metadata":{"accession":"PF20186","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR046679","hierarchy":null,"name":{"name":"Family of unknown function (DUF6549)","short":"DUF6549"},"description":[{"text":"<p>This presumed domain is functionally uncharacterised. This domain family is mainly found in bacteria, and is typically between 120 and 180 amino acids in length. There are two highly conserved residues, an aspartate and a tryptophan, and a NP conserved motif.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":3,"interactions":0,"matches":85,"pathways":0,"proteins":85,"proteomes":73,"sets":0,"structural_models":{"alphafold":59},"structures":0,"taxa":193},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":10,"alignment:full":87},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}