{"metadata":{"accession":"PF19988","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR046309","hierarchy":null,"name":{"name":"Family of unknown function (DUF6424)","short":"DUF6424"},"description":[{"text":"<p>This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000379) is described by MIBiG as an example of the following biosynthetic class, NRP (non-ribosomal peptide), in particular the glycinocin A biosynthetic gene cluster from streptomyces viridochromogenes [[cite:PUB00099403]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00099403":{"PMID":21640802,"ISBN":null,"volume":"483","issue":"1-2","year":2011,"title":"Molecular cloning and identification of the laspartomycin biosynthetic gene cluster from Streptomyces viridochromogenes.","URL":null,"raw_pages":"11-21","medline_journal":"Gene","ISO_journal":"Gene","authors":["Wang Y","Chen Y","Shen Q","Yin X."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":68,"pathways":0,"proteins":67,"proteomes":66,"sets":0,"structural_models":{"alphafold":30},"structures":0,"taxa":94},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":11,"alignment:full":32},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}