This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001916) is described by MIBiG as an example of the following biosynthetic class, polyketide, in particular the lavendiol biosynthetic gene cluster from Streptomyces lavendulae [[cite:PUB00098885]].
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00098885":{"PMID":29255990,"ISBN":null,"volume":"45","issue":"2","year":2018,"title":"Discovery of a new diol-containing polyketide by heterologous expression of a silent biosynthetic gene cluster from Streptomyces lavendulae FRI-5.","URL":null,"raw_pages":"77-87","medline_journal":"J Ind Microbiol Biotechnol","ISO_journal":"J Ind Microbiol Biotechnol","authors":["Pait IGU","Kitani S","Roslan FW","Ulanova D","Arai M","Ikeda H","Nihira T."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":21,"pathways":0,"proteins":21,"proteomes":17,"sets":0,"structural_models":{"alphafold":6},"structures":0,"taxa":43},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":2,"alignment:full":8},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}