{"metadata":{"accession":"PF19980","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR046301","hierarchy":null,"name":{"name":"Family of unknown function (DUF6416)","short":"DUF6416"},"description":[{"text":"<p>This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001300) is described by MIBiG as an example of the following biosynthetic class, polyketide, in particular the anthracimycin biosynthetic gene cluster from Streptomyces sp. CNH365 [[cite:PUB00099456]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00099456":{"PMID":26348978,"ISBN":null,"volume":"10","issue":"11","year":2015,"title":"Two of a Kind--The Biosynthetic Pathways of Chlorotonil and Anthracimycin.","URL":null,"raw_pages":"2480-90","medline_journal":"ACS Chem Biol","ISO_journal":"ACS Chem Biol","authors":["Jungmann K","Jansen R","Gerth K","Huch V","Krug D","Fenical W","Muller R."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":5,"interactions":0,"matches":65,"pathways":0,"proteins":65,"proteomes":64,"sets":0,"structural_models":{"alphafold":32},"structures":0,"taxa":124},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":6,"alignment:full":30},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}