{"metadata":{"accession":"PF19941","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR045645","hierarchy":null,"name":{"name":"Family of unknown function (DUF6403)","short":"DUF6403"},"description":[{"text":"<p>This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001447) is described by MIBiG as an example of the following biosynthetic class, polyketide, in particular the primycin biosynthetic gene cluster from Saccharomonospora azurea SZMC 14600 [[cite:PUB00098889],[cite:PUB00098888]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00098889":{"PMID":22328759,"ISBN":null,"volume":"194","issue":"5","year":2012,"title":"Draft genome sequence of an efficient antibiotic-producing industrial strain of Saccharomonospora azurea, SZMC 14600.","URL":null,"raw_pages":"1263","medline_journal":"J Bacteriol","ISO_journal":"J Bacteriol","authors":["Csepregi K","Valasek A","Penzes A","Toth Z","Kiss EI","Kerepesi I","Horvath B","Nagy I","Fekete C."],"DOI_URL":null},"PUB00098888":{"PMID":28000508,"ISBN":null,"volume":"67","issue":"4","year":2016,"title":"Proteomic insight into the primycin fermentation process of Saccharomonospora azurea.","URL":null,"raw_pages":"424-430","medline_journal":"Acta Biol Hung","ISO_journal":"Acta Biol Hung","authors":["Valasek A","Kiss IE","Fodor I","Kovacs M","Urban P","Jambor E","Fekete C","Kerepesi I."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":97,"pathways":0,"proteins":97,"proteomes":96,"sets":0,"structural_models":{"alphafold":64},"structures":0,"taxa":137},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":27,"alignment:full":39},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}