This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000755) is described by MIBiG as an example of the following biosynthetic class, saccharide, in particular the capsular polysaccharide biosynthetic gene cluster from Avibacterium paragallinarum 221 [[cite:PUB00098895]]. This family appears to be predominantly found in Actinobacteria and Firmicutes.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00098895":{"PMID":20362405,"ISBN":null,"volume":"145","issue":"1-2","year":2010,"title":"Analysis of the biosynthesis genes and chemical components of the capsule of Avibacterium paragallinarum.","URL":null,"raw_pages":"90-9","medline_journal":"Vet Microbiol","ISO_journal":"Vet Microbiol","authors":["Wu JR","Chen PY","Shien JH","Shyu CL","Shieh HK","Chang F","Chang PC."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":3,"interactions":0,"matches":166,"pathways":0,"proteins":166,"proteomes":163,"sets":0,"structural_models":{"alphafold":95},"structures":0,"taxa":273},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":17,"alignment:full":78},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}