{"metadata":{"accession":"PF19902","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR045955","hierarchy":null,"name":{"name":"Family of unknown function (DUF6375)","short":"DUF6375"},"description":[{"text":"<p>This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001020) is described by MIBiG as an example of the following biosynthetic classes, NRP (non-ribosomal peptide) and polyketide, in particular the muraymycin C1 biosynthetic gene  cluster from Streptomyces sp. NRRL 30471 [[cite:PUB00099464]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00099464":{"PMID":21180767,"ISBN":null,"volume":"7","issue":"3","year":2011,"title":"Identification of the gene cluster involved in muraymycin biosynthesis from Streptomyces sp. NRRL 30471.","URL":null,"raw_pages":"920-7","medline_journal":"Mol Biosyst","ISO_journal":"Mol Biosyst","authors":["Cheng L","Chen W","Zhai L","Xu D","Huang T","Lin S","Zhou X","Deng Z."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":74,"pathways":0,"proteins":74,"proteomes":72,"sets":0,"structural_models":{"alphafold":35},"structures":0,"taxa":237},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":4,"alignment:full":27},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}