{"metadata":{"accession":"PF19897","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR045950","hierarchy":null,"name":{"name":"Family of unknown function (DUF6370)","short":"DUF6370"},"description":[{"text":"<p>This family of proteins is found in bacteria and it is functionally uncharacterised. Proteins in this family are approximately 110 amino acids in length. Some of the members included in this family are thought to be glutaminyl-tRNA synthetases. There are some conserved sequence motifs: CGxC, YFVD/EG and GDAH.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":406,"pathways":0,"proteins":406,"proteomes":402,"sets":0,"structural_models":{"alphafold":252},"structures":0,"taxa":512},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":41,"alignment:full":145},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}