{"metadata":{"accession":"PF19884","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR045937","hierarchy":null,"name":{"name":"Family of unknown function (DUF6357)","short":"DUF6357"},"description":[{"text":"<p>This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000368) is described by MIBiG as an example of the following biosynthetic class, NRP (non-ribosomal peptide), in particular the streptobactin biosynthetic gene cluster from Streptomyces sp. ATCC 700974 [[cite:PUB00099408]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00099408":{"PMID":19915026,"ISBN":null,"volume":"192","issue":"2","year":2010,"title":"Gene cluster involved in the biosynthesis of griseobactin, a catechol-peptide siderophore of Streptomyces sp. ATCC 700974.","URL":null,"raw_pages":"426-35","medline_journal":"J Bacteriol","ISO_journal":"J Bacteriol","authors":["Patzer SI","Braun V."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":153,"pathways":0,"proteins":152,"proteomes":133,"sets":0,"structural_models":{"alphafold":78},"structures":0,"taxa":207},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":16,"alignment:full":76},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}