{"metadata":{"accession":"PF19874","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR045928","hierarchy":null,"name":{"name":"Family of unknown function (DUF6347)","short":"DUF6347"},"description":[{"text":"<p>This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001130) is described by MIBiG as an example of the following biosynthetic classes, NRP (non-ribosomal peptide) and polyketide, in particular the fabclavine Ia biosynthetic gene  cluster from Xenorhabdus budapestensis [[cite:PUB00099452]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00099452":{"PMID":24532262,"ISBN":null,"volume":"15","issue":"4","year":2014,"title":"Fabclavines: bioactive peptide-polyketide-polyamino hybrids from Xenorhabdus.","URL":null,"raw_pages":"512-6","medline_journal":"Chembiochem","ISO_journal":"Chembiochem","authors":["Fuchs SW","Grundmann F","Kurz M","Kaiser M","Bode HB."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":15,"pathways":0,"proteins":15,"proteomes":15,"sets":0,"structural_models":{"alphafold":11},"structures":0,"taxa":31},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":1,"alignment:full":3},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}