This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001615) is described by MIBiG as an example of the following biosynthetic class, NRP (non-ribosomal peptide), in particular hexose-palythine-serine biosynthetic gene cluster from Heteroscytonema crispum UCFS10 [[cite:PUB00099381]].
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00099381":{"PMID":27474710,"ISBN":null,"volume":"82","issue":"19","year":2016,"title":"Comparative Profiling and Discovery of Novel Glycosylated Mycosporine-Like Amino Acids in Two Strains of the Cyanobacterium Scytonema cf. crispum.","URL":null,"raw_pages":"5951-9","medline_journal":"Appl Environ Microbiol","ISO_journal":"Appl Environ Microbiol","authors":["D'Agostino PM","Javalkote VS","Mazmouz R","Pickford R","Puranik PR","Neilan BA."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":152,"pathways":0,"proteins":151,"proteomes":140,"sets":0,"structural_models":{"alphafold":95},"structures":0,"taxa":422},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":23,"alignment:full":133},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}