{"metadata":{"accession":"PF19856","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR046294","hierarchy":null,"name":{"name":"Family of unknown function (DUF6331)","short":"DUF6331"},"description":[{"text":"<p>This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001060) is described by MIBiG as an example of the following biosynthetic class, polyketide, in particular the  dynemicin A biosynthetic gene cluster from Micromonospora chersina  [[cite:PUB00078772]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00078772":{"PMID":18328078,"ISBN":null,"volume":"282","issue":"1","year":2008,"title":"The biosynthetic genes encoding for the production of the dynemicin enediyne core in Micromonospora chersina ATCC53710.","URL":null,"raw_pages":"105-14","medline_journal":"FEMS Microbiol Lett","ISO_journal":"FEMS Microbiol. Lett.","authors":["Gao Q","Thorson JS."],"DOI_URL":"http://dx.doi.org/10.1111/j.1574-6968.2008.01112.x"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":3,"interactions":0,"matches":101,"pathways":0,"proteins":101,"proteomes":100,"sets":0,"structural_models":{"alphafold":60},"structures":0,"taxa":244},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":8,"alignment:full":36},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}