{"metadata":{"accession":"PF19831","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR046279","hierarchy":null,"name":{"name":"Family of unknown function (DUF6312)","short":"DUF6312"},"description":[{"text":"<p>This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001772) is described by MIBiG as an example of the following biosynthetic class, polyketide, in particular the  scytophycin biosynthetic gene cluster from Anabaena sp. UHCC 0451 [[cite:PUB00099384]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00099384":{"PMID":29150506,"ISBN":null,"volume":"84","issue":"3","year":2018,"title":"The Swinholide Biosynthesis Gene Cluster from a Terrestrial Cyanobacterium, Nostoc sp. Strain UHCC 0450.","URL":null,"raw_pages":null,"medline_journal":"Appl Environ Microbiol","ISO_journal":"Appl Environ Microbiol","authors":["Humisto A","Jokela J","Liu L","Wahlsten M","Wang H","Permi P","Machado JP","Antunes A","Fewer DP","Sivonen K."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":6,"interactions":0,"matches":48,"pathways":0,"proteins":48,"proteomes":36,"sets":0,"structural_models":{"alphafold":24},"structures":0,"taxa":121},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":9,"alignment:full":18},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}