{"metadata":{"accession":"PF19810","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR046260","hierarchy":null,"name":{"name":"HFX_2341-like, N-terminal","short":"HFX_2341_N"},"description":[{"text":"<p>This domain is found at the N-terminal of HFX_2341 from Haloferax mediterranei and similar archaeal proteins. HFX_2341 is a global regulator involved in cas gene regulation. This domain contains a conserved sequence motif HxxPxxG and a conserved asparagine residue. It is often found associated with [pfam:PF22665].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00155412":{"PMID":39338447,"ISBN":null,"volume":"12","issue":"9","year":2024,"title":"A Haloarchaeal Transcriptional Regulator That Represses the Expression of CRISPR-Associated Genes.","URL":null,"raw_pages":"1772","medline_journal":"Microorganisms","ISO_journal":"Microorganisms","authors":["Turgeman-Grott I","Shalev Y","Shemesh N","Levy R","Eini I","Pasmanik-Chor M","Gophna U."],"DOI_URL":"https://doi.org/10.3390/microorganisms12091772"}},"set_info":{"accession":"CL0236","name":"PDDEXK"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":13,"interactions":0,"matches":697,"pathways":0,"proteins":687,"proteomes":395,"sets":1,"structural_models":{"alphafold":644},"structures":0,"taxa":718},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":42,"alignment:full":307},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}