{"metadata":{"accession":"PF19808","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR046258","hierarchy":null,"name":{"name":"Family of unknown function (DUF6291)","short":"DUF6291"},"description":[{"text":"<p>This family of proteins, found in bacteria and viruses, is functionally uncharacterised. Proteins in this family are typically between 179 and 275 amino acids in length. There are two conserved residues, a leucine and a tyrosine.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":9,"interactions":0,"matches":197,"pathways":0,"proteins":197,"proteomes":158,"sets":0,"structural_models":{"alphafold":100},"structures":0,"taxa":356},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":44,"alignment:full":145},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}