{"metadata":{"accession":"PF19806","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR046256","hierarchy":null,"name":{"name":"Family of unknown function (DUF6289)","short":"DUF6289"},"description":[{"text":"<p>This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000385) is described by MIBiG as an example of the following biosynthetic class, NRP (non-ribosomal peptide), in  particular the lysobactin biosynthetic gene cluster from  Lysobacter sp. ATCC 53042 [[cite:PUB00098898]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00098898":{"PMID":21609846,"ISBN":null,"volume":"18","issue":"5","year":2011,"title":"Identification and characterization of the lysobactin biosynthetic gene cluster reveals mechanistic insights into an unusual termination module architecture.","URL":null,"raw_pages":"655-64","medline_journal":"Chem Biol","ISO_journal":"Chem Biol","authors":["Hou J","Robbel L","Marahiel MA."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":344,"pathways":0,"proteins":344,"proteomes":187,"sets":0,"structural_models":{"alphafold":185},"structures":0,"taxa":307},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":27,"alignment:full":147},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}