{"metadata":{"accession":"PF19784","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR046236","hierarchy":null,"name":{"name":"Family of unknown function (DUF6269)","short":"DUF6269"},"description":[{"text":"<p>This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001975) is described by MIBiG as an example of the following biosynthetic class, NRP (non-ribosomal peptide). It  includes a member from the atratumycin biosynthetic gene cluster  from Streptomyces atratus [[cite:PUB00099465]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00099465":{"PMID":30746943,"ISBN":null,"volume":"21","issue":"5","year":2019,"title":"Genome Mining of Streptomyces atratus SCSIO ZH16: Discovery of Atratumycin and Identification of Its Biosynthetic Gene Cluster.","URL":null,"raw_pages":"1453-1457","medline_journal":"Org Lett","ISO_journal":"Org Lett","authors":["Sun C","Yang Z","Zhang C","Liu Z","He J","Liu Q","Zhang T","Ju J","Ma J."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":29,"pathways":0,"proteins":29,"proteomes":27,"sets":0,"structural_models":{"alphafold":10},"structures":0,"taxa":42},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":4,"alignment:full":11},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}