This family of proteins, functionally uncharacterised, is found in bacteria. Proteins in this family are typically between 124 and 143 amino acids in length. Some members included in this family are hypothetical transposases, associated with transposon Tn554 [[cite:PUB00099532]]. There is a conserved sequence GV/LSR/K and a highly conserved tyrosine residue.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00099532":{"PMID":2846290,"ISBN":null,"volume":"7","issue":"9","year":1988,"title":"Transposon Tn554 encodes three products required for transposition.","URL":null,"raw_pages":"2935-41","medline_journal":"EMBO J","ISO_journal":"EMBO J","authors":["Bastos MC","Murphy E."],"DOI_URL":null}},"set_info":{"accession":"CL0123","name":"HTH"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":5,"interactions":0,"matches":1089,"pathways":0,"proteins":1089,"proteomes":809,"sets":1,"structural_models":{"alphafold":607},"structures":0,"taxa":1414},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":24,"alignment:full":524},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}