{"metadata":{"accession":"PF19768","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR046222","hierarchy":null,"name":{"name":"Family of unknown function (DUF6255)","short":"DUF6255"},"description":[{"text":"<p>This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001662) is described by MIBiG as an example of the following biosynthetic class, polyketide. It includes a member from the mediomycin A biosynthetic gene cluster from Kitasatospora  mediocidica [[cite:PUB00099386]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00099386":{"PMID":29349495,"ISBN":null,"volume":"102","issue":"5","year":2018,"title":"Genomic-driven discovery of an amidinohydrolase involved in the biosynthesis of mediomycin A.","URL":null,"raw_pages":"2225-2234","medline_journal":"Appl Microbiol Biotechnol","ISO_journal":"Appl Microbiol Biotechnol","authors":["Sun F","Xu S","Jiang F","Liu W."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":76,"pathways":0,"proteins":76,"proteomes":31,"sets":0,"structural_models":{"alphafold":28},"structures":0,"taxa":52},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":4,"alignment:full":24},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}