{"metadata":{"accession":"PF19762","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR046216","hierarchy":null,"name":{"name":"Domain of unknown function (DUF6249)","short":"DUF6249"},"description":[{"text":"<p>This domain family is found in bacterial proteins, functionally uncharacterised. Proteins in this family are typically between 174 and 239 amino acids in length. This domain is thought to contain transmembrane regions. This family is distantly related to [pfam:PF11239].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":1429,"pathways":0,"proteins":1429,"proteomes":1251,"sets":0,"structural_models":{"alphafold":934},"structures":0,"taxa":1894},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":91,"alignment:full":799},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}