This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001133) is described by MIBiG as an example of the following biosynthetic class, NRP (non-ribosomal peptide). It includes a member from the taxlllaid A biosynthetic gene cluster from Xenorhabdus bovienii SS-2004 [[cite:PUB00098918]]. This family appears to be predominantly found in Proteobacteria.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00098918":{"PMID":25351611,"ISBN":null,"volume":"20","issue":"52","year":2014,"title":"Characterisation of taxlllaids A-G; natural products from Xenorhabdus indica.","URL":null,"raw_pages":"17478-87","medline_journal":"Chemistry","ISO_journal":"Chemistry","authors":["Kronenwerth M","Bozhuyuk KA","Kahnt AS","Steinhilber D","Gaudriault S","Kaiser M","Bode HB."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":45,"pathways":0,"proteins":45,"proteomes":23,"sets":0,"structural_models":{"alphafold":35},"structures":0,"taxa":59},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":11,"alignment:full":19},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}