This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001485) is described by MIBiG as an example of the following biosynthetic class, other (unspecified). It includes a member from the 3-demethylchuangxinmycin biosynthetic gene cluster from Actinoplanes tsinanensis [[cite:PUB00099369]]. This family appears to be predominantly found in Actinobacteria.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00099369":{"PMID":27405170,"ISBN":null,"volume":"51","issue":"1","year":2016,"title":"[Identification of 3-demethylchuangxinmycin from Actinoplanes tsinanensis CPCC 200056].","URL":null,"raw_pages":"105-9","medline_journal":"Yao Xue Xue Bao","ISO_journal":"Yao Xue Xue Bao","authors":["Zuo LJ","Zhao W","Jiang ZB","Jiang BY","Li SF","Liu HY","Yu LY","Hong B","Hu XX","You XF","Wu LZ."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":3,"interactions":0,"matches":189,"pathways":0,"proteins":155,"proteomes":139,"sets":0,"structural_models":{"alphafold":65},"structures":0,"taxa":187},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":9,"alignment:full":74},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}