This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001418) is described by MIBiG as an example of the following biosynthetic classes, NRP (non-ribosomal peptide) and polyketide. This family includes a protein from the myxochromide D biosynthetic gene cluster from Hyalangium minutum and appears to be predominantly found in Cystobacterineae[[cite:PUB00098945]].
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00098945":{"PMID":28128551,"ISBN":null,"volume":"12","issue":"3","year":2017,"title":"Genomics-Guided Exploitation of Lipopeptide Diversity in Myxobacteria.","URL":null,"raw_pages":"779-786","medline_journal":"ACS Chem Biol","ISO_journal":"ACS Chem Biol","authors":["Burgard C","Zaburannyi N","Nadmid S","Maier J","Jenke-Kodama H","Luxenburger E","Bernauer HS","Wenzel SC."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":42,"pathways":0,"proteins":42,"proteomes":42,"sets":0,"structural_models":{"alphafold":27},"structures":0,"taxa":66},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":2,"alignment:full":13},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}