{"metadata":{"accession":"PF19508","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR046105","hierarchy":null,"name":{"name":"Family of unknown function (DUF6042)","short":"DUF6042"},"description":[{"text":"<p>This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000291) is described by MIBiG as an example of the following biosynthetic class, NRP (non-ribosomal peptide). This family includes a protein from the A54145 biosynthetic gene cluster  from Streptomyces fradiae [[cite:PUB00099441]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00099441":{"PMID":16208464,"ISBN":null,"volume":"33","issue":"2","year":2006,"title":"The lipopeptide antibiotic A54145 biosynthetic gene cluster from Streptomyces fradiae.","URL":null,"raw_pages":"129-40","medline_journal":"J Ind Microbiol Biotechnol","ISO_journal":"J Ind Microbiol Biotechnol","authors":["Miao V","Brost R","Chapple J","She K","Gal MF","Baltz RH."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":3,"interactions":0,"matches":210,"pathways":0,"proteins":209,"proteomes":197,"sets":0,"structural_models":{"alphafold":124},"structures":0,"taxa":309},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":22,"alignment:full":108},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}