This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000758) is described by MIBiG as an example of the following biosynthetic class, saccharide. This family includes a protein from the capsular polysaccharide biosynthetic gene cluster from Staphylococcus aureus [[cite:PUB00007578]].
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00007578":{"PMID":7961465,"ISBN":null,"volume":"176","issue":"22","year":1994,"title":"Sequence analysis and molecular characterization of genes required for the biosynthesis of type 1 capsular polysaccharide in Staphylococcus aureus.","URL":null,"raw_pages":"7005-16","medline_journal":"J Bacteriol","ISO_journal":"J. Bacteriol.","authors":["Lin WS","Cunneen T","Lee CY."],"DOI_URL":"http://ukpmc.ac.uk/articlerender.cgi?tool=EBI&pubmedid=7961465"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":33,"pathways":0,"proteins":33,"proteomes":15,"sets":0,"structural_models":{"alphafold":25},"structures":0,"taxa":34},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":2,"alignment:full":4},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}