This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000919) is described by MIBiG as an example of the following biosynthetic class, other (unspecified). This family includes a protein from the phaseolotoxin biosynthetic gene cluster from Pseudomonas syringae and appears to be predominantly found in bacteria [[cite:PUB00099406]].
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00099406":{"PMID":17237165,"ISBN":null,"volume":"189","issue":"7","year":2007,"title":"Functional characterization of the gene cluster from Pseudomonas syringae pv. phaseolicola NPS3121 involved in synthesis of phaseolotoxin.","URL":null,"raw_pages":"2834-43","medline_journal":"J Bacteriol","ISO_journal":"J Bacteriol","authors":["Aguilera S","Lopez-Lopez K","Nieto Y","Garciduenas-Pina R","Hernandez-Guzman G","Hernandez-Flores JL","Murillo J","Alvarez-Morales A."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":34,"pathways":0,"proteins":34,"proteomes":29,"sets":0,"structural_models":{"alphafold":19},"structures":0,"taxa":83},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":7,"alignment:full":14},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}