This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001285) is described by MIBiG as an example of the following biosynthetic class, other (unspecified). This family includes a protein from the pseudopyronine A biosynthetic gene cluster from Pseudomonas putida and appears to be predominantly found in Pseudomonas [[cite:PUB00099447]].
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00099447":{"PMID":26507104,"ISBN":null,"volume":"16","issue":"17","year":2015,"title":"Biosynthetic Origin of the Antibiotic Pseudopyronines A and B in Pseudomonas putida BW11M1.","URL":null,"raw_pages":"2491-7","medline_journal":"Chembiochem","ISO_journal":"Chembiochem","authors":["Bauer JS","Ghequire MG","Nett M","Josten M","Sahl HG","De Mot R","Gross H."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":222,"pathways":0,"proteins":222,"proteomes":222,"sets":0,"structural_models":{"alphafold":85},"structures":0,"taxa":244},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":3,"alignment:full":15},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}