{"metadata":{"accession":"PF19482","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR046060","hierarchy":null,"name":{"name":"Family of unknown function (DUF6018)","short":"DUF6018"},"description":[{"text":"<p>This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000320) is described by MIBiG as an example of the following biosynthetic class, NRP (non-ribosomal peptide). This  family includes a protein from the cereulide biosynthetic gene  cluster from Bacillus cereus and appears to be predominantly found  in Bacilli [[cite:PUB00099383],[cite:PUB00099443]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00099383":{"PMID":15640177,"ISBN":null,"volume":"71","issue":"1","year":2005,"title":"Identification and partial characterization of the nonribosomal peptide synthetase gene responsible for cereulide production in emetic Bacillus cereus.","URL":null,"raw_pages":"105-13","medline_journal":"Appl Environ Microbiol","ISO_journal":"Appl Environ Microbiol","authors":["Ehling-Schulz M","Vukov N","Schulz A","Shaheen R","Andersson M","Martlbauer E","Scherer S."],"DOI_URL":null},"PUB00099443":{"PMID":16512902,"ISBN":null,"volume":"6","issue":null,"year":2006,"title":"Cereulide synthetase gene cluster from emetic Bacillus cereus: structure and location on a mega virulence plasmid related to Bacillus anthracis toxin plasmid pXO1.","URL":null,"raw_pages":"20","medline_journal":"BMC Microbiol","ISO_journal":"BMC Microbiol","authors":["Ehling-Schulz M","Fricker M","Grallert H","Rieck P","Wagner M","Scherer S."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":20,"pathways":0,"proteins":20,"proteomes":18,"sets":0,"structural_models":{"alphafold":16},"structures":0,"taxa":40},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":2,"alignment:full":8},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}