{"metadata":{"accession":"PF19475","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR046054","hierarchy":null,"name":{"name":"Family of unknown function (DUF6012)","short":"DUF6012"},"description":[{"text":"<p>This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000128) is described by MIBiG as an example of the following biosynthetic class, polyketide. This family includes a  protein encoded by the pyoluteorin biosynthetic gene cluster from  Pseudomonas sp. M18 [[cite:PUB00099395],[cite:PUB00099404]]</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00099395":{"PMID":15033239,"ISBN":null,"volume":"232","issue":"2","year":2004,"title":"Identification and characterization of pltZ, a gene involved in the repression of pyoluteorin biosynthesis in Pseudomonas sp. M18.","URL":null,"raw_pages":"197-202","medline_journal":"FEMS Microbiol Lett","ISO_journal":"FEMS Microbiol Lett","authors":["Huang X","Zhu D","Ge Y","Hu H","Zhang X","Xu Y."],"DOI_URL":null},"PUB00099404":{"PMID":16581203,"ISBN":null,"volume":"376","issue":"1","year":2006,"title":"Identification and characterization of a putative ABC transporter PltHIJKN required for pyoluteorin production in Pseudomonas sp. M18.","URL":null,"raw_pages":"68-78","medline_journal":"Gene","ISO_journal":"Gene","authors":["Huang X","Yan A","Zhang X","Xu Y."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":71,"pathways":0,"proteins":71,"proteomes":63,"sets":0,"structural_models":{"alphafold":41},"structures":0,"taxa":169},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":5,"alignment:full":14},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}