{"metadata":{"accession":"PF19473","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR046052","hierarchy":null,"name":{"name":"Family of unknown function (DUF6010)","short":"DUF6010"},"description":[{"text":"<p>This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001011) is described by MIBiG as an example of the following biosynthetic classes, NRP (non-ribosomal peptide) and polyketide. This family includes a protein from the meridamycin  biosynthetic gene cluster from Streptomyces sp. NRRL 30748 [[cite:PUB00099405]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00099405":{"PMID":16806745,"ISBN":null,"volume":"377","issue":null,"year":2006,"title":"Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.","URL":null,"raw_pages":"109-18","medline_journal":"Gene","ISO_journal":"Gene","authors":["He M","Haltli B","Summers M","Feng X","Hucul J."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":537,"pathways":0,"proteins":537,"proteomes":529,"sets":0,"structural_models":{"alphafold":301},"structures":0,"taxa":908},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":40,"alignment:full":235},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}