This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001814) is described by MIBiG as an example of the following biosynthetic class, NRP (non-ribosomal peptide). This family includes a protein from the ulleungmycin biosynthetic gene cluster from Streptomyces sp. KCB13F003 [[cite:PUB00099461]].
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00099461":{"PMID":9083895,"ISBN":null,"volume":"17","issue":"2","year":1997,"title":"Concentrations of soluble CD95 and CD8 antigens in the plasma and levels of CD8+CD95+, CD8+CD38+, and CD4+CD95+ T cells are markers for HIV-1 infection and clinical status.","URL":null,"raw_pages":"185-92","medline_journal":"J Clin Immunol","ISO_journal":"J Clin Immunol","authors":["Jiang JD","Schlesinger M","Sacks H","Mildvan D","Roboz JP","Bekesi JG."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":2104,"pathways":0,"proteins":2104,"proteomes":2088,"sets":0,"structural_models":{"alphafold":1131},"structures":0,"taxa":2396},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":135,"alignment:full":970},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}