This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001890) is described by MIBiG as an example of the following biosynthetic class, NRP (non-ribosomal peptide). The exemplar is the amphi-enterobactin 1 biosynthetic gene cluster from Vibrio campbellii [[cite:PUB00099429]].
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00099429":{"PMID":29954861,"ISBN":null,"volume":"115","issue":"29","year":2018,"title":"Quorum sensing and iron regulate a two-for-one siderophore gene cluster in Vibrio harveyi.","URL":null,"raw_pages":"7581-7586","medline_journal":"Proc Natl Acad Sci U S A","ISO_journal":"Proc Natl Acad Sci U S A","authors":["McRose DL","Baars O","Seyedsayamdost MR","Morel FMM."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":4,"interactions":0,"matches":146,"pathways":0,"proteins":146,"proteomes":142,"sets":0,"structural_models":{"alphafold":93},"structures":0,"taxa":297},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":31,"alignment:full":67},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}