This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000838) is described by MIBiG as an example of the following biosynthetic class, polyketide, in particular the flexirubin biosynthetic gene cluster from Flavobacterium johnsoniae. This protein has no known function. It is found in Actinobacteria, Proteobacteria and Bacteroidetes. Proteins in this family are typically between 234 and 271 amino acids in length.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":4,"interactions":0,"matches":147,"pathways":0,"proteins":146,"proteomes":143,"sets":0,"structural_models":{"alphafold":96},"structures":0,"taxa":308},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":47,"alignment:full":67},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}