{"metadata":{"accession":"PF19367","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR045987","hierarchy":null,"name":{"name":"Domain of unknown function (DUF5943)","short":"DUF5943"},"description":[{"text":"<p>This presumed domain is functionally uncharacterised. This domain family is found in proteobacteria and sporadically in archaea, and is approximately 100 amino acids in length. There are two conserved sequence motifs: NNH and RLS. This domain is often found to the N-terminus of [pfam:PF02830].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":900,"pathways":0,"proteins":900,"proteomes":875,"sets":0,"structural_models":{"alphafold":533},"structures":0,"taxa":1119},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":7,"alignment:full":232},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}