{"metadata":{"accession":"PF19343","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR045967","hierarchy":null,"name":{"name":"HAM1-like, N-terminal domain","short":"HAM1_N"},"description":[{"text":"<p>This entry represents a domain found at the N-terminal end of the putative cell signalling protein HAM1 from Cryptococcus neoformans and similar fungal sequences. HAM1 may act as a negative regulator of mating during vegetative growth [[cite:PUB00155454]]. Proteins with this domain often also contain a C-terminal domain [pfam:PF14613].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00155454":{"PMID":38842336,"ISBN":null,"volume":"12","issue":"7","year":2024,"title":"Phenotypic characterization of <i>HAM1</i>, a novel mating regulator of the fungal pathogen <i>Cryptococcus neoformans</i>.","URL":null,"raw_pages":"e0341923","medline_journal":"Microbiol Spectr","ISO_journal":"Microbiol Spectr","authors":["Arsenault Yee E","Ross RL","Santiago-Tirado FH."],"DOI_URL":"https://doi.org/10.1128/spectrum.03419-23"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":59,"interactions":0,"matches":4050,"pathways":0,"proteins":2939,"proteomes":1323,"sets":0,"structural_models":{"alphafold":2413},"structures":0,"taxa":2830},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":117,"alignment:full":3692},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}