{"metadata":{"accession":"PF19138","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR043859","hierarchy":null,"name":{"name":"Transcriptional regulator TbsP-like, N-terminal","short":"TbsP_N"},"description":[{"text":"<p>This domain is found at the N-terminal of the putative transcriptional regulator TbsP from Halobacterium volcanii ([swissprot:D4GXF9], also known as HVO_2861) and similar sequences predominantly found in Halobacteria. TbsP is required for adhesion to abiotic surfaces (i.e., biofilm formation) and maintains wild-type cell morphology and motility. This domain shows weak structural similarity with the DNA -binding protein TrmBL2 of P. furiosus ([pfam:PF11495]) [[cite:PUB00153356]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00153356":{"PMID":38204420,"ISBN":null,"volume":null,"issue":null,"year":2024,"title":"TbsP and TrmB jointly regulate gapII to influence cell development phenotypes in the archaeon Haloferax volcanii.","URL":null,"raw_pages":null,"medline_journal":"Mol Microbiol","ISO_journal":"Mol Microbiol","authors":["Hackley RK","Hwang S","Herb JT","Bhanap P","Lam K","Vreugdenhil A","Darnell CL","Pastor MM","Martin JH","Maupin-Furlow JA","Schmid AK."],"DOI_URL":"https://doi.org/10.1111/mmi.15225"}},"set_info":{"accession":"CL0479","name":"PLD"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":4,"interactions":0,"matches":429,"pathways":0,"proteins":428,"proteomes":279,"sets":1,"structural_models":{"alphafold":403},"structures":0,"taxa":435},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":102,"alignment:full":182},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}