{"metadata":{"accession":"PF19021","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR043959","hierarchy":null,"name":{"name":"CRISPR system CMR subunit Cmr7 1","short":"Cmr7A"},"description":[{"text":"<p>The CRISPR-Cas system is a prokaryotic defense mechanism against foreign genetic elements. The key elements of this defense system are the Cas proteins and the CRISPR RNA. In the CRISPR-Cas system, RNA is targeted by the CMR complex. In Sulfolobus solfataricus this complex is composed of seven CAS protein subunits (Cmr1-7) and carries a diverse \"payload\" of targeting crRNA. This entry represent the Cmr7 subunit of the CMR complex [[cite:PUB00094641]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00094641":{"PMID":22227115,"ISBN":null,"volume":"45","issue":"3","year":2012,"title":"Structure and mechanism of the CMR complex for CRISPR-mediated antiviral immunity.","URL":null,"raw_pages":"303-13","medline_journal":"Mol Cell","ISO_journal":"Mol. Cell","authors":["Zhang J","Rouillon C","Kerou M","Reeks J","Brugger K","Graham S","Reimann J","Cannone G","Liu H","Albers SV","Naismith JH","Spagnolo L","White MF."],"DOI_URL":null}},"set_info":{"accession":"CL0278","name":"AIG2"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":6,"pathways":0,"proteins":6,"proteomes":6,"sets":1,"structural_models":{"alphafold":6},"structures":8,"taxa":19},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":1,"alignment:full":2},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}