{"metadata":{"accession":"PF18645","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR040833","hierarchy":null,"name":{"name":"Family of unknown function (DUF5631)","short":"DUF5631"},"description":[{"text":"<p>This is an alpha helical domain found at the C-terminal region of the hypothetical protein Rv3899c from Mycobacterium tuberculosis which is conserved across mycobacteria [[cite:PUB00091180]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00091180":{"PMID":27487929,"ISBN":null,"volume":"72","issue":"Pt 8","year":2016,"title":"Crystal structure of Rv3899c(184-410), a hypothetical protein from Mycobacterium tuberculosis.","URL":null,"raw_pages":"642-5","medline_journal":"Acta Crystallogr F Struct Biol Commun","ISO_journal":"Acta Crystallogr F Struct Biol Commun","authors":["Liu Y","Gao Y","Li D","Fleming J","Li H","Bi L."],"DOI_URL":"https://doi.org/10.1107/S2053230X16010943"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":314,"pathways":0,"proteins":314,"proteomes":146,"sets":0,"structural_models":{"alphafold":219},"structures":1,"taxa":168},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":58,"alignment:full":97},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}