This is a domain of unknown function predicted to be a carbohydrate binding module [[cite:PUB00091246]].
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00091246":{"PMID":27298375,"ISBN":null,"volume":"113","issue":"26","year":2016,"title":"Complexity of the Ruminococcus flavefaciens cellulosome reflects an expansion in glycan recognition.","URL":null,"raw_pages":"7136-41","medline_journal":"Proc Natl Acad Sci U S A","ISO_journal":"Proc. Natl. Acad. Sci. U.S.A.","authors":["Venditto I","Luis AS","Rydahl M","Schuckel J","Fernandes VO","Vidal-Melgosa S","Bule P","Goyal A","Pires VM","Dourado CG","Ferreira LM","Coutinho PM","Henrissat B","Knox JP","Basle A","Najmudin S","Gilbert HJ","Willats WG","Fontes CM."],"DOI_URL":"https://doi.org/10.1073/pnas.1601558113"}},"set_info":{"accession":"CL0202","name":"GBD"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":5,"interactions":0,"matches":17,"pathways":0,"proteins":10,"proteomes":4,"sets":1,"structural_models":{"alphafold":9},"structures":3,"taxa":22},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":13,"alignment:full":15},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"4v1k","name":"SeMet structure of a novel carbohydrate binding module from glycoside hydrolase family 9 (Cel9A) from Ruminococcus flavefaciens FD-1"}}}