This is a domain of unknown function found in bacteria and archaea.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00050844":{"PMID":18361456,"ISBN":null,"volume":"71","issue":"4","year":2008,"title":"Crystal structure of a novel non-Pfam protein AF1514 from Archeoglobus fulgidus DSM 4304 solved by S-SAD using a Cr X-ray source.","URL":null,"raw_pages":"2109-13","medline_journal":"Proteins","ISO_journal":"Proteins","authors":["Li Y","Bahti P","Shaw N","Song G","Chen S","Zhang X","Zhang M","Cheng C","Yin J","Zhu JY","Zhang H","Che D","Xu H","Abbas A","Wang BC","Liu ZJ."],"DOI_URL":"http://dx.doi.org/10.1002/prot.22025"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":73,"pathways":0,"proteins":73,"proteomes":56,"sets":0,"structural_models":{"alphafold":68},"structures":1,"taxa":162},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":57,"alignment:full":68},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"3c0f","name":"Crystal Structure of a novel non-Pfam protein AF1514 from Archeoglobus fulgidus DSM 4304 solved by S-SAD using a Cr X-ray source"}}}