{"metadata":{"accession":"PF18356","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR041574","hierarchy":null,"name":{"name":"Domain of unknown function (DUF5608)","short":"DUF5608"},"description":[{"text":"<p>This entry represents a domain from ORF137 from Pyrobaculum spherical virus. This protein contains two domains with Sm-like fold which relative orientation is very similar to the relative orientation of individual subunits in the Sm-like assembly rings.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00054436":{"PMID":20419351,"ISBN":null,"volume":"11","issue":"2","year":2010,"title":"The Scottish Structural Proteomics Facility: targets, methods and outputs.","URL":null,"raw_pages":"167-80","medline_journal":"J Struct Funct Genomics","ISO_journal":"J. Struct. Funct. Genomics","authors":["Oke M","Carter LG","Johnson KA","Liu H","McMahon SA","Yan X","Kerou M","Weikart ND","Kadi N","Sheikh MA","Schmelz S","Dorward M","Zawadzki M","Cozens C","Falconer H","Powers H","Overton IM","van Niekerk CA","Peng X","Patel P","Garrett RA","Prangishvili D","Botting CH","Coote PJ","Dryden DT","Barton GJ","Schwarz-Linek U","Challis GL","Taylor GL","White MF","Naismith JH."],"DOI_URL":"http://dx.doi.org/10.1007/s10969-010-9090-y"}},"set_info":{"accession":"CL0986","name":"Sm-like"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":1,"pathways":0,"proteins":1,"proteomes":1,"sets":1,"structural_models":{"alphafold":1},"structures":1,"taxa":8},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":1,"alignment:full":1},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}