{"metadata":{"accession":"PF18120","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR040719","hierarchy":null,"name":{"name":"Domain of unknown function (DUF5597)","short":"DUF5597"},"description":[{"text":"<p>This is the C-terminal domain of xyloglucan utilization locus (XyGUL) present in Cellvibrio japonicas. XyGUL is required for xyloglucan utilization. It is also the C-terminal domain of PF02449 and PF01301 [[cite:PUB00091233]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00091233":{"PMID":25171165,"ISBN":null,"volume":"94","issue":"2","year":2014,"title":"A complex gene locus enables xyloglucan utilization in the model saprophyte Cellvibrio japonicus.","URL":null,"raw_pages":"418-33","medline_journal":"Mol Microbiol","ISO_journal":"Mol. Microbiol.","authors":["Larsbrink J","Thompson AJ","Lundqvist M","Gardner JG","Davies GJ","Brumer H."],"DOI_URL":"https://doi.org/10.1111/mmi.12776"}},"set_info":{"accession":"CL0369","name":"GHD"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":19,"interactions":0,"matches":1630,"pathways":0,"proteins":1630,"proteomes":1157,"sets":1,"structural_models":{"alphafold":1116},"structures":18,"taxa":2018},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":45,"alignment:full":1047},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}