This is a family of unknown function found in chordata. Family members contain a transmembrane region in the C-terminal and have been shown to be localized to the Golgi apparatus [[cite:PUB00091556]].
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00091556":{"PMID":24312644,"ISBN":null,"volume":"8","issue":"12","year":2013,"title":"C11ORF24 is a novel type I membrane protein that cycles between the Golgi apparatus and the plasma membrane in Rab6-positive vesicles.","URL":null,"raw_pages":"e82223","medline_journal":"PLoS One","ISO_journal":"PLoS ONE","authors":["Fraisier V","Kasri A","Miserey-Lenkei S","Sibarita JB","Nair D","Mayeux A","Bardin S","Toyoda Y","Poser I","Poznyakovskiy A","Goud B","Hyman AA","Dimitrov A."],"DOI_URL":"https://doi.org/10.1371/journal.pone.0082223"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":28,"pathways":0,"proteins":28,"proteomes":19,"sets":0,"structural_models":{"alphafold":27},"structures":0,"taxa":79},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":1,"alignment:full":27},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}