{"metadata":{"accession":"PF17721","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR037655","hierarchy":null,"name":{"name":"POU domain class 2-associating factor 2","short":"POU2AF2"},"description":[{"text":"<p>POU domain class 2-associating factor 2 (also known as Protein OCA-T1) is a transcriptional coactivator that specifically associates with POU2F3 [[cite:PUB00101325]], forming a complex that drives the development of tuft cells, a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues [[cite:PUB00101325]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00101325":{"PMID":35576971,"ISBN":null,"volume":"607","issue":"7917","year":2022,"title":"OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage.","URL":null,"raw_pages":"169-175","medline_journal":"Nature","ISO_journal":"Nature","authors":["Wu XS","He XY","Ipsaro JJ","Huang YH","Preall JB","Ng D","Shue YT","Sage J","Egeblad M","Joshua-Tor L","Vakoc CR."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":8,"interactions":0,"matches":616,"pathways":0,"proteins":608,"proteomes":446,"sets":0,"structural_models":{"alphafold":520},"structures":0,"taxa":1498},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":18,"alignment:full":481},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}