{"metadata":{"accession":"PF17555","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR035177","hierarchy":null,"name":{"name":"Type VI secretion system, TssN","short":"TssN"},"description":[{"text":"<p>T6SSs are toxin delivery systems. It is a multiprotein complex requiring numerous core proteins (Tss proteins) including cytoplasmic, transmembrane, and outer membrane components. The needle or tube apparatus is comprised of a phage-like complex, similar to the T4 contractile bacteriophage tail, which is thought to be anchored to the membrane by a trans-envelope complex [[cite:PUB00090998]]. TssN proteins have multiple predicted transmembrane (TM) regions. In Flavobacterium johnsoniae, three specific components (TssN, TssO and TssP) are absent in the other sub-types of T6SS [[cite:PUB00090999]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00090999":{"PMID":26979785,"ISBN":null,"volume":"6","issue":null,"year":2016,"title":"Identification of protein secretion systems in bacterial genomes.","URL":null,"raw_pages":"23080","medline_journal":"Sci Rep","ISO_journal":"Sci Rep","authors":["Abby SS","Cury J","Guglielmini J","Neron B","Touchon M","Rocha EP."],"DOI_URL":"https://doi.org/10.1038/srep23080"},"PUB00090998":{"PMID":26768901,"ISBN":null,"volume":"17","issue":null,"year":2016,"title":"Type VI secretion systems of human gut Bacteroidales segregate into three genetic architectures, two of which are contained on mobile genetic elements.","URL":null,"raw_pages":"58","medline_journal":"BMC Genomics","ISO_journal":"BMC Genomics","authors":["Coyne MJ","Roelofs KG","Comstock LE."],"DOI_URL":"https://doi.org/10.1186/s12864-016-2377-z"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":536,"pathways":0,"proteins":536,"proteomes":484,"sets":0,"structural_models":{"alphafold":345},"structures":0,"taxa":654},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":15,"alignment:full":180},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}