{"metadata":{"accession":"PF17238","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR035192","hierarchy":null,"name":{"name":"NUP160, helical domain","short":"NUP160_helical_2"},"description":[{"text":"<p>This entry represents a helical domain that can be found in NUP160, also known as SAR1, a nucleoporin protein in Arabidopsis thaliana. It is a member of the NUP107-160 nuclear pore sub-complex [[cite:PUB00085245]]. NUP160 plays a role in normal auxin signalling, which works in synergy with ethylene to control various ethylene-dependent phenomena [[cite:PUB00155768]]. Also, it contributes to pathogen defense [[cite:PUB00085247]], nucleocytoplasmic mRNA export [[cite:PUB00155768]], and is required for disease resistance [[cite:PUB00085246]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00085245":{"PMID":22288649,"ISBN":null,"volume":"70","issue":"5","year":2012,"title":"Putative members of the Arabidopsis Nup107-160 nuclear pore sub-complex contribute to pathogen defense.","URL":null,"raw_pages":"796-808","medline_journal":"Plant J","ISO_journal":"Plant J.","authors":["Wiermer M","Cheng YT","Imkampe J","Li M","Wang D","Lipka V","Li X."],"DOI_URL":"https://doi.org/10.1111/j.1365-313X.2012.04928.x"},"PUB00085247":{"PMID":22238449,"ISBN":null,"volume":"63","issue":"5","year":2012,"title":"A loss-of-function mutation in the nucleoporin AtNUP160 indicates that normal auxin signalling is required for a proper ethylene response in Arabidopsis.","URL":null,"raw_pages":"2231-41","medline_journal":"J Exp Bot","ISO_journal":"J. Exp. Bot.","authors":["Robles LM","Deslauriers SD","Alvarez AA","Larsen PB."],"DOI_URL":"https://doi.org/10.1093/jxb/err424"},"PUB00155768":{"PMID":36598573,"ISBN":null,"volume":"42","issue":"3","year":2023,"title":"The nucleoporin NUP160 and NUP96 regulate nucleocytoplasmic export of mRNAs and participate in ethylene signaling and response in Arabidopsis.","URL":null,"raw_pages":"549-559","medline_journal":"Plant Cell Rep","ISO_journal":"Plant Cell Rep","authors":["Nie Y","Li Y","Liu M","Ma B","Sui X","Chen J","Yu Y","Dong CH."],"DOI_URL":"https://doi.org/10.1007/s00299-022-02976-6"},"PUB00085246":{"PMID":22902705,"ISBN":null,"volume":"7","issue":"10","year":2012,"title":"Nucleoporins Nup160 and Seh1 are required for disease resistance in Arabidopsis.","URL":null,"raw_pages":"1212-4","medline_journal":"Plant Signal Behav","ISO_journal":"Plant Signal Behav","authors":["Roth C","Wiermer M."],"DOI_URL":"https://doi.org/10.4161/psb.21426"}},"set_info":{"accession":"CL0833","name":"Nup120_hel_sf"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":31,"interactions":0,"matches":619,"pathways":0,"proteins":611,"proteomes":352,"sets":1,"structural_models":{"alphafold":101},"structures":1,"taxa":989},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":12,"alignment:full":387},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}