{"metadata":{"accession":"PF16335","entry_id":null,"type":"repeat","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR032514","hierarchy":null,"name":{"name":"Glutaminase A six helical-hairpin domain","short":"GtaA_6_Hairpin"},"description":[{"text":"<p>This entry represents the six helical-hairpin domain found in homologues of Glutaminase A from Aspergillus oryzae. Glutaminase catalyzes the hydrolysis of glutamine to glutamic acid and plays a key role in nitrogen metabolism. It catalyzes the hydrolysis not only of L-glutamine but also of D-glutamine [[cite:PUB00035385]]. This domain share similarity with six-hairpin glycosidases.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00035385":{"PMID":10952006,"ISBN":null,"volume":"54","issue":"1","year":2000,"title":"Molecular cloning and characterization of a gene encoding glutaminase from Aspergillus oryzae.","URL":null,"raw_pages":"59-68","medline_journal":"Appl Microbiol Biotechnol","ISO_journal":"Appl. Microbiol. Biotechnol.","authors":["Koibuchi K","Nagasaki H","Yuasa A","Kataoka J","Kitamoto K."],"DOI_URL":"http://dx.doi.org/10.1007/s002530000329"}},"set_info":{"accession":"CL0059","name":"6_Hairpin"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":90,"interactions":0,"matches":5628,"pathways":0,"proteins":4215,"proteomes":1856,"sets":1,"structural_models":{"alphafold":3216},"structures":0,"taxa":3600},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":72,"alignment:full":4293},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}