{"metadata":{"accession":"PF16155","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR032345","hierarchy":null,"name":{"name":"4-hydroxylaminobenzoate lyase","short":"PnbB"},"description":[{"text":"<p>This family, previously known as DUF4863, represents 4-hydroxylaminobenzoate lyase (PnbB) and related proteins mainly found in various proteobacteria, but also several fungal species. PnbB catalyses the conversion of 4-hydroxylaminobenzoate to 3,4-dihydroxybenzoate (protocatechuate) and ammonium. This enzyme is involved in the degradation of nitroaromatic compounds [[cite:PUB00158932],[cite:PUB00114928]]. Proteins from this family have a cupin-like fold and may be related to a group of lyases involved in the metabolism of benzoate.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00114928":{"PMID":11157934,"ISBN":null,"volume":"183","issue":"4","year":2001,"title":"Cloning and characterization of the pnb genes, encoding enzymes for 4-nitrobenzoate catabolism in Pseudomonas putida TW3.","URL":null,"raw_pages":"1225-32","medline_journal":"J Bacteriol","ISO_journal":"J Bacteriol","authors":["Hughes MA","Williams PA."],"DOI_URL":null},"PUB00158932":{"PMID":34554625,"ISBN":null,"volume":"23","issue":"11","year":2021,"title":"The low-nanomolar 4-nitrobenzoate-responsive repressor PnbX negatively regulates the actinomycete-derived 4-nitrobenzoate-degrading pnb locus.","URL":null,"raw_pages":"7028-7041","medline_journal":"Environ Microbiol","ISO_journal":"Environ Microbiol","authors":["Cheng M","Qian Y","Xing Z","Zylstra GJ","Huang X."],"DOI_URL":"https://doi.org/10.1111/1462-2920.15787"}},"set_info":{"accession":"CL0029","name":"Cupin"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":16,"interactions":0,"matches":854,"pathways":0,"proteins":851,"proteomes":764,"sets":1,"structural_models":{"alphafold":601},"structures":0,"taxa":1350},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":18,"alignment:full":506},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}